[DOWNLOAD] "Talasemi Minor Tanisindaki Zorluklar/Difficulties in Diagnosing Thalassemia Minor (Cagnli Editor/Invited Editor) (Clinical Report)" by Turkish Pediatrics Archive " Book PDF Kindle ePub Free

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eBook details

Title: Talasemi Minor Tanisindaki Zorluklar/Difficulties in Diagnosing Thalassemia Minor (Cagnli Editor/Invited Editor) (Clinical Report)
Author : Turkish Pediatrics Archive
Release Date : January 01, 2009
Genre: Health & Fitness,Books,Health, Mind & Body,
Pages : * pages
Size : 75 KB

Description

Normal bir eriskinde, hemoglobin (Hb) A, Hb F ve Hb [A.sub.2] olmak uzere 3 farkli hemoglobin tipi bulunur. Hemoglobin A (Eriskin hemoglobini); 2 alfa ([alpha]), 2 beta ([beta]) zincirinden olusmakta olup eriskin kaninda %96-98 oraninda bulunur. Hemoglobin A2; 2 [alpha], 2 delta ([delta]) zincirinden olusur ve %3,4'e kadar normal dir. Fetusun hemoglobini olan Hb F ise 2 alfa, 2 gama ([gamma]) zincirinden olusur, dogumdan sonra giderek azalir, bir yasindan sonra %2'yi gecmez (1). Talasemi sendromlan, oldukca genis genetik cesitlilik gostermekte olup, sentezi bozulmus olan globin zincirine gore [alpha], [beta], [gamma], [delta], [delta[[beta], [epsilon][gamma][delta][beta], talasemi olarak adlandirilir. Klinikte onemli olan ve en sik gorulen talasemiler, [alpha] ve [beta] globin genleri ile ilgili [alpha] ve [beta] talasemilerdir (2).